Cannabinoid 1 Receptor stable expressing HEK293 Cell Line
Description
CB1 Cannabinoid Receptor Cell Line contains HEK293 cells stably expressing CB1 with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual. The CB1 Cell Line allows to assay compounds, or analyze their capability to modulate CB1. When a ligand binds to the CB1, it activates a G protein, which in turn, triggers a cellular response mediated by a second messenger. HiTSeeker CB1 cell line has been validated performing an assay with [3H]CP55940 and increasing concentrations of no radioactive competitor. The high reproducibility of this assay allows monitoring CB1 receptor activation process in High Throughput Screening.
Internal Reference:
SA-CAS9-143
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