Enabling Tools & Strategeis: LC/MS & Ion Mobility
“Morrow, K.J., "Making stride in protein characterization," Genetic Engineering & Biotechnology News 31, pages 24, 26 (Fenruary 1, 2011).
MS Tags
“Mass tags quantify glycosylation,” C&EN 88, pages 37-38 (August 2, 2010).
The Versatility of MS
Morrow, K.J., “Mass Spectometry's Role in Discovery on the Rise,” Genetic Engineering & Biotechnology News 30, pages 1, 22, 24 (May 15, 2010).
The Application Notebook
"Biological, Drugs of Abuse, Environmental, Food & Beverages, Pharmaceutical, General," see "The Application Notebook", Supplement to LC GC (August 2002).
Web sites
Proteomics Technology: | |
Genomics | A research Pointer to Proteomics & Scientific IT Resources |
Bioinformatics: | Bioarrays: |
The Latest News & Product Info | Proteinchemist.com: |
Data Overload
Shaffer, C., “New tools for dealing with data overload,” Genetic Engineering & Biotechnology News 30, pages 20, 24-25, (April 15, 2010).
Careers in Proteomics
Henry, C. M., “Careers for 2002 and Beyond: Proteomics, The job market for protein biochemists with interdisciplinary savvy is on the upswing,” C & EN80, pages 69-70, 72, 75, (2002).
Metabolomics
Morrow, K.J., “Mass spec central to metabolomics,"Genetic Engineering & Biotechnology News 30, pages 1, 24 (January 15, 2006).
Characterization of N-Linked Glycans
Bynum, B., Baginski, T., Keck, R., Killeen, K., "Integrated microfluidic LC/MS," Pharmaceutical Technology, pages s32-s36, s38-s39 (Supplement to march 2010 Issue)
2-D Gel-LC/MS vs LC/LC/MS/MS: Biomakers & Drug Discovery
Duncan, M.W., "Proteomics-based biomaker & drug discovery," Genetic Engineering & Biotechnology News 26, pages 20, 23 (January 15, 2006).
Biomaker Strategies: Index of Companies with Proteomics-Enabling Tools & Technoliges
Glaser, V., "Applying biomaker discovery strategies," Genetic Engineering News 26, pages 36, 38 (January 1, 2006).
MS: Plasma Biomakers
Marusina, K.,, "A new spin on plasma biomaker discovery," Genetic Engineering News 25, pages 27, 28 (November 2005).
MS: The Technique of Choice For Protein Identification
Morrow, K.J., "Applying mass spec tools in proteomics," Genetic Engineering News 25, pages 1, 12, 14 (September 2005).
DNA Biomarkers
Rodriguez, H., "Technologies and standards used in the measurement of DNA biomarkers for the safety of tissue-engineered medical products," American Pharmaceutical Review 8, pages 67-70 (2005).
Are Ions Generated by ES Significantly Different than those Produced by MALDI?
Jonscher, K., "Proteomics: To spray or not to spray," Genomics & Proteomics 3, pages 31-33 (2003).
The Verbs of Proteomics
Czernik, A.J., Browning, M.D., Haycock, J.W., "Phosphoproteins: The Verbs of the Proteomic Language," Bioscience Technolgy 28, pages 8, 10, 14 (2003).
Making [ES & MALDI] FT/MS Mainstream!
MacNeil, J.S., "Making FT/MS Matter," Genome Technology, pages 34-38, 40 (June 2003).
MS Rules Proteomics
Jonscher, K., "Reshaping proteomics with mass spectrometry," Genomics & Proteomics 3, pages 25-28 (2003).
Proteins & Their Environment
Willis, R.C., "Interfacing with the proteome," Today's Chemist at Work 12, pages 27-28, 30, 32 (2003).
Quantitative Analysis
Karnes, H.T., "Validation and control of quantitative bioanalytical LC/MS methods, American Pharmaceutical Review 6, pages 106, 108, (2003).
LC-LC
Wehr, T., "Multidimensional liquid chromatography in proteomic studies," LC GC Europe 16, pages 154, 156-158. 160-162 (2003).
High-Throughput and Protein Analysis
Griffin, T.J., Han, D.K.M., Gygi, S.P., Rist, B., Lee, H., Aebersold, R., Parker, K.C., "Toward a high-throughput approach to quantitative proteomic analysis: Expression-dependent protein idnetification by mass spectrometry, J. Am. Soc. Mass Spectrom. 12, pages 1238-1246 (2002).
Proteomics Select
The virtual Journal of Proteomics
MALDI, Atmospheric MALDI & LC/MS
Musselman, B., Jonscher, K., "Emerging liquid chromatography-MALDI: Enabling high-throughput capability," American Genomic/Proteomic Technology 2, pages 22, 24-27 (July/August 2002).
New Technology for Proteomics
Stevenson, R., "PITTCON'02 offers new technology for proteomics," American Genomic/Proteomic Technology 2, pages 6-11 (July/August 2002).
Sample Prep for Genomics
Majors, R. E., "Automation of Sample Preparation for Genomics," LC GC 20, pages 416,420, 422, 424, 428, 428 (2002).
Analytical Chemists Look Into Their Crystal Balls to Glimpse Future Instrumentation [MS] Needs
Borman, S., “From the ACS Meeting: Millennial Analysis,” C & EN 80, pages 49-50, 52 (2002).
Product Review: Software for MS Protein Identification
Handley, J., "Software for MS Protein Identification", Anal. Chem. 74, pages 159A- 162A (2002).
LC/MS/MS: Ion Mobility-IonTrap-Q-TOF for Protein Identity
Hoaglund-Hyzer, C. S., Lee, Y. J., Counterman, A. E., Clemmer, D. E., "Coupling Ion Mobility Separations, Collisional Activation Techniques, and Multiple Stages of MS for Analysis of Complex Peptide Mixtures", Anal. Chem. 74, pages 929-1006 (2002).
LC/MS: Ion Mobility-TOF for Protein Identity
Developing a Robust Reversed-Phase Method for the Analysis of Polypeptides
Grace/Vydac (The Separation Group) (1995).
The Handbook of Analysis & Purification of Peptides & Proteins by Reverse-Phase HPLC
Grace/Vydac (The Separation Group) (1995).
Automation & Robotics
R&D Magazine (January 2002).
Practical Application
Review of the sessions at HPLC 2001 related to Proteomics, Genomics, & Metabolomics
Separation & Proteomics
Mass Spectrometry & Proteomics
IT & Proteomics
Hancock, W. S., "Contribution of ion trap mass spectrometry to proteomics", American Laboratory 33, pages 18, 20-21 (June 2001).
LC/MS/MS
Proteomics
Columns & Electrospray LC/MS, Part I & Part II
Mechanisms of Fragmentation of Peptides Analyzed by MALDI-PSD-MS & ES-CAD-MS/MS
..Technology Can Have a Greater Impact on Error Reduction than Human Behavior Modification
Protein Structure
Ion Suppression: The most common reason for assay failure!!!
"Look Mom No More Gels"
"Proteomics"
Protein Sequencing
Tuning Electrospray for Protein Analysis
Adduct Scanning Algorithm
Effects of LC Chemical Composition on ESI
Mass Spectrometer Imaging
Genomic/Proteomic Analysis: HPLC, MALDI & ESI
Electrospray-FTMS [ES-MS/MS] Method Improves Cell Protein Analysis
Electrospray-FTMS Mild Fragmentation with Electron Capture Dissociation (ECD)
Rapid Desalting Dialyzer for Mass Spectrometry
MS & DNA
Peptides & Proteins
Diagnostic Sequencing of DNA by [MALDI-TOF] Mass Spectrometry
Identification of the Oxidation States of the Active Site Cysteine in a Recombinant Protein Tyrosine Phosphatase by Electrospray Mass Spectrometry Using On-Line Desalting
Mass Spec Meets Biotech: Maldi TOF-MS is Expediting New Research in Application such as Foodborne Illnesses
Mass Spectrometry in Trace Analysis
Tandem FTMS of Large Biomolecules
Applications of ESI [electrospray] Mass Spectrometry in Biology
Applications of Mass Spectrometry to the Characterization of Oligonucleotides & Nucleic Acids
MS & the Age of Proteome [proteins & genes]
Probing Viruses with Mass Spectrometry
Sample Preparation for LC/MS/MS: Analyzing Biological & Environmental Samples
Covalently Modified Proteins: pages 691R-692R
Disulfide Bonds: pages 689R
Gels, Mass Mapping, Sequencing & Data Base Interrogation: pages 686R-688R
Oligonucleotides & Nucleic Acids: pages 692R-698R
Peptides & Proteins: pages 681R-686R
Phosphorylation: pages 689R-690R
Post-Tranlational Modification: pages 688R-689R
Current Practice of Liquid Chromatography-Mass Spectrometry
Hydroxyl Radical Induced Hydrogen/Deutrium Exchange in Amino Acid Carbon-Hydrogen Bonds
Characteization of Labeled Oligonucleotides Using Enzymatic Digestion and Tandem Mass Spectrometry
Mass Spectral Identification and Positional Mapping of Aflatoxin B1-Guanine Adducts in Oligonucleotides
Stucture and Fragmentation Mechanisms of Isomeric T-Rich Oligodeoxynucleotides: A Comparison of Four Tandem Mass Spectrometric Methods
Time, Life ... and Mass Spectrometry: New Techniques to Address Biological Questions
MALDI MS & Strategies for Protein Analysis
Tandem-in-Time MS as a Quantitative Bioanalytical Tool
Mass Spectrometry [Electrospray & MALDI] as a Readout of Protein Structure and Function
Emerging Tandem-Mass Spectrometry [MS/MS] Techniques for the Rapid Identification of Proteins
The Influence of Strongly Acidic Groups on the Protonation of Peptides in Electrospray MS
Separation and Analysis of Peptides and Protein: Liquid Chromatography
Separation and Analysis of Peptides and Proteins: Mass Spectrometry
Separation and Analysis of Peptides and Proteins: Mass Spectrometry as a Detector for Protein and Peptide Separations.
Determination of Amino Acid Isotope Ratios by Electrospray Ionization-Mass Spectrometry
The Handbook of Analysis & Purification of Peptides & Proteins by Reverse-Phase HPLC
Vydac Techical Support Broup (1995).
MS/MS Applications in Biological Problems.
Favretto, D., Traldi, P., Mass Spectrom. Rev. 12, pages 313-395 (1993).
Analysis of Peptide Mixtures by Capillary High Performance Liquid Chromatography: A Practical Guide to Small-Scale Separations
Mass Spectrometry
Chapter 18, Selected Applications (In: Liquid Chromatography-Mass Spectrometry: Principles and Applications)
Integration of Mass Spectrometry in Analytical Biotechnology
Liquid Chromatography/Mass Spectrometry: Techniques and Applications
LC/MS Update and Soft Ionization (a bimonthly international journal)
HD Science, 242 N. James Street, Tower Office Park, Suite 202, Newport, Wilmington, DE 19804-3168, USA, Phone: 302-994-8026, Fax: 302-994-8837.