AP-MALDI

AP-MALDI Sources and Components

Since being founded in 1995, Chem-Space Associates has a major objective to development enabling technologies the are intended to facilitate the growth of LC/MS. We have concentrated our research and development in areas that will increase the efficiency and sensitivity of LC/MS systems. We also recognized that a small business does not have the engineering resources or the product distribution capabilities to compete at the system level in LC/MS. Our choice has been to focus and special on areas of technology development that provide high value to the market. Our efforts have primarily been directed at atmospheric pressure optics (where significant inefficiencies are observed) and source development where we feel there is a need for more sensitivity, higher specificity, and increased dynamic range.

Figure 1- Simulation of Back-Well AP-MALDI geometry where sample is applied directly onto the front of the instrument and ions are sampled through annular optics into an optical well located "behind" the sample target surface.